Rolac 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 55.21
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Renata limited |
| Also available as |
Title
- Rolac
- Ketorolac Tromethamine
Categories
- Pain Management
- Ophthalmic Solution
- NSAID
- Analgesic
- Nonsteroidal Anti-Inflammatory Drug
- Rheumatoid Arthritis Medication
Description
- Short-term management of moderate to severe acute post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
Chemical Composition
- Pyrrolo-pyrrole group
- 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- 2 - amino-2-(hydroxymethyl)-1,3-propanediol
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Associated with the S-form
- Linear pharmacokinetic property
- Highly protein bound
- Metabolized in the liver
- Urinary excretion of metabolites
Mode of Action
- Inhibits the cyclooxygenase enzyme system
- Inhibits prostaglandin synthesis
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose of 10 mg every 4-6 hours
- Injection recommended for moderately severe acute pain
- Dosage varies based on age and condition
- Specific dosages for different age groups and routes of administration
- Max duration of oral and parenteral treatment
- Dosage for eye drops
Interactions
- Increased side effects with other NSAIDs or aspirin
- Enhanced anticoagulant effect with anticoagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Not for use in children under 16 years
- Not to be used as prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastrointestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- Pregnancy category C
- Avoid use in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Caution for use of eye drops with corneal epithelial breakdown
- Avoid use while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis Medication
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children