Surpim 10 mg (Tablet)
Unit Price: ৳ 10.00 (20's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Asiatic laboratories ltd |
| Also available as |
Indications
- Management of acute post-operative pain
- Relief of pain and inflammation after ocular surgery
- Reduction of eye inflammation caused by allergies
Description
- Pyrrolo-pyrrole group NSAID
- Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- Linear pharmacokinetic property
- Highly protein-bound
- Liver metabolism
- Urinary excretion
Pharmacology
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet: Recommended dose of 10 mg every 4-6 hours for short-term use
- Injection: Recommended doses for single and multiple doses based on age and condition
- Eye Drops: Adult dosage of 1 drop in each eye 4 times daily
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with Beta Blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to the drug or other NSAIDs
- Not for use in children under 16 years of age
- Contraindicated as prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoid use in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Discontinue use in case of corneal epithelial breakdown
- Avoid use with contact lenses
Therapeutic Class
- Rheumatoid Arthritis drugs
- Non-Opioid Analgesics
Storage Conditions
- Store in dry place away from light and heat
- Keep out of the reach of children