Toralin 10 mg (Tablet)
Unit Price: ৳ 10.07 (3 x 10: ৳ 302.10)
Strip Price: ৳ 100.70
Medicine Details
Category | Details |
---|---|
Generic | Ketorolac tromethamine |
Company | Nipro jmi pharma ltd |
Indications
- Short-term management of post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decreasing eye inflammation or redness caused by allergies
Description
- Drug of pyrrolo-pyrrole group of NSAID
- Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- Inhibits prostaglandin synthesis
- Peripherally acting analgesic
- Highly protein bound and metabolized in liver
Pharmacology
- Potent analgesic NSAID
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours
- Injection for moderately severe acute pain management
- Specific dosages for different age groups and conditions
- Maximum daily doses for different populations
- Recommended duration of treatment
- Eye drops dosage
Interaction
- NSAIDs and aspirin increase side effects of Toralin
- Anti-coagulants enhance anti-coagulant effect
- Beta Blockers reduce anti-hypertensive effect
- ACE Inhibitors increase risk of renal impairment
- Methotrexate enhances toxicity of methotrexate
Contraindications
- Hypersensitivity to the drug or other NSAIDs
- Not recommended for children under 16 years of age
- Contraindicated as a prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melana
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- US FDA Pregnancy category C
- Avoid use during pregnancy and lactation unless benefits outweigh risks to fetus
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Special precautions for patients using eye drops and wearing contact lenses
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children