Toradolin 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 140.00 (1 x 5: ৳ 700.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Title
- Toradolin
Categories
- Pain Management
- Ophthalmic Solutions
- Nonsteroidal Anti-inflammatory Drugs
- Analgesics
- NSAIDs
Description
- Short-term management of moderate to severe acute post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
Chemical Composition
- Pyrolo-pyrrole group
- Nonsteroidal anti-inflammatory drug (NSAID)
- 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- 2 - amino-2-(hydroxymethyl)-1,3-propanediol
Pharmacological Action
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Potent analgesic of the NSAIDs
- Inhibits cyclooxygenase enzyme system
- Demonstrates minimal anti-inflammatory effect
Dosage
- Tablet dose: 10 mg every 4-6 hours
- Injection dose: single or multiple doses for acute pain management
- IV bolus must be given over no less than 15 seconds
- IM administration should be given slowly and deeply into the muscle
- Eye drops: 1 drop in each eye 4 times daily
Interactions
- NSAIDs or aspirin increase side effects of Toradolin
- Anti-coagulants enhance anti-coagulant effect
- Beta Blockers reduce the anti-hypertensive effect
- ACE Inhibitors increase the risk of renal impairment
- Methotrexate enhances the toxicity of methotrexate
Contraindications
- Hypersensitivity to drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years of age
- Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Discontinue use of topical NSAIDs in patients with corneal epithelial breakdown
- Avoid administering while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children