Viroxi 200 mg (Tablet)
Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir oral |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Treatment of viral infections due to Herpes simplex virus (type I & II) and Varicella zoster virus
- Treatment of Herpes simplex virus infections of the skin and mucous membranes
- Prophylaxis of Herpes simplex infections in immunocompromised patients
Pharmacology
- Synthetic purine derivative
- Interferes with DNA synthesis and inhibits viral replication
- Converted to Aciclovir Triphosphate for antiviral activity
- 15-30% oral absorption
- Widely distributed in body tissues and fluids
- Excreted through kidney
Dosage & Administration
- Treatment of initial herpes simplex: 200 mg 5 times daily usually for 5 days
- 400 mg 5 times daily for 5 days for immunocompromised patients (adults)
- Prevention of recurrence of herpes simplex: 200 mg 4 times daily or 400 mg twice daily
- Prophylactic treatment of herpes simplex in immunocompromised patients: 200 to 400 mg 4 times daily
- Treatment of vericella (chicken pox): 800 mg 4 times daily for 5 days (adults)
- 800 mg 5 times daily for 7 days for treatment of herpes zoster (shingles)
Interaction
- Probenecid reduces Aciclovir excretion and increases plasma concentration
Contraindications
- Hypersensitivity to Aciclovir
Side Effects
- Rash
- Gastrointestinal disturbance
- Rise in bilirubin and liver-related enzymes
- Increase in blood urea and creatinine
- Decrease in hematological indices
- Headache
- Neurological reactions
- Fatigue
Pregnancy & Lactation
- Pregnancy category B
- Use during pregnancy requires careful consideration of benefit vs. risk
- Use caution when administered to nursing mothers
Precautions & Warnings
- Administer with caution in patients with renal impairment
- Dose adjustment based on creatinine clearance
- Monitor neutrophil count at least twice weekly in neonates
Therapeutic Class
- Herpes simplex & Varicella-zoster virus infections
Storage Conditions
- Should be stored below 25°C
- Protected from light and moisture
- Keep out of the reach of children