Torolac 10 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Silva pharmaceuticals ltd |
Title
- Ketorolac
- Torolac
Categories
- Nonsteroidal Anti-Inflammatory Drug (NSAID)
- Analgesic
- Ophthalmic Solution
Description
- Ketorolac is a pyrrolo-pyrrole group NSAID
- Chemical name: 5 Benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- Metabolized in the liver
- Biological activity associated with S-form
- Highly protein-bound
- Pharmacokinetic property is linear
Pharmacology
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage and administration
- Tablet dosage: 10 mg every 4-6 hours
- Injection dosage: Single or multiple doses for postoperative pain management
- Duration of analgesic effect: 4 to 6 hours
- Eye drops dosage: 1 drop in each eye 4 times daily
Interaction
- Interaction with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to drug or other NSAIDs
- Contraindicated in children under 16 years
- Not for use as prophylactic analgesic before surgery
Side effects
- Nausea
- Vomiting
- Gastrointestinal bleeding
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy and lactation
- US FDA Pregnancy category: C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions and warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Discontinue use of ophthalmic solution in case of corneal breakdown
- Avoid administering ophthalmic solution with contact lenses on
Therapeutic class
- Rheumatoid Arthritis drugs
- Non-Opioid Analgesics
Storage conditions
- Keep in a dry place away from light and heat
- Keep out of reach of children