Tromark 10 mg (Tablet)
Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Hallmark pharmaceuticals ltd |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease in eye inflammation or redness caused by seasonal allergies
Description
- Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Highly protein bound
- Metabolized in the liver
Pharmacology
- Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
- Inhibits the cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at its analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours for short-term use (up to 7 days)
- Injection administered as single or multiple doses for postoperative pain management
- IV bolus given over no less than 15 seconds
- Duration of analgesic effect is usually 4 to 6 hours
- Dosage differs for patients of different ages and conditions
Interaction
- Other NSAIDs or aspirin increase the side effects of Tromark
- Anti-coagulants enhance anti-coagulant effect
- Beta Blockers reduce the anti-hypertensive effect
- ACE Inhibitors increase the risk of renal impairment
- Methotrexate enhances the toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Not recommended for children under 16 years of age
- Contraindicated as prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- Pregnancy category C
- Avoid during pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Exercise caution in patients over 65 years of age
- Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use of topical NSAIDs in patients with corneal epithelial breakdown
- Do not administer ophthalmic solution while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children