Winop 10 mg (Tablet)

Unit Price: ৳ 12.00 (2 x 10: ৳ 240.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Acme laboratories ltd
Also available as
Winop 30 mg injection Winop 60 mg injection

Indications

  • Short-term management of post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Inhibits synthesis of prostaglandins
  • Associated with the S-form
  • Linear pharmacokinetic property
  • Highly protein bound
  • Mainly metabolized in the liver
  • Metabolites and some unchanged drugs are excreted in urine

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Recommended tablet dose: 10mg every 4-6 hours for up to 7 days
  • Injection may be administered as single or multiple doses
  • Analgesic effect begins within 30 minutes
  • Maximum effect reached in 1 to 2 hours
  • Duration of analgesic effect is usually 4 to 6 hours
  • Storage condition: Keep in a dry place away from light and heat

Interaction

  • Other NSAIDs or aspirin can increase side effects of Winop
  • Anti-coagulants can enhance anti-coagulant effect
  • Beta Blockers can reduce the anti-hypertensive effect
  • ACE Inhibitors can increase the risk of renal impairment
  • Methotrexate can enhance the toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Not to be used in children under 16 years of age
  • Contraindicated as prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • US FDA Pregnancy category: C
  • Should be avoided in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • Eye Drops: Should not be administered while wearing contact lenses

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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