Zeropain 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 60.00 (1 x 5: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decreasing eye inflammation or redness caused by seasonal allergies
Category
- Nonsteroidal anti-inflammatory drug (NSAID)
- Ophthalmic solution
- Analgesic
- Anti-inflammatory
Chemical Composition
- Pyrrolo-pyrrole group
- 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- 2-amino-2-(hydroxymethyl)-1,3-propanediol
Pharmacological Action
- Inhibition of prostaglandin synthesis
- Minimal anti-inflammatory effect
Dosage & Administration
- Tablet: 10 mg every 4-6 hours, up to 7 days
- Injection: Single or multiple doses
- Eye Drops: 1 drop in each eye 4 times daily
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with Beta Blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- Pregnancy category C
- Avoidance in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years of age
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use of topical NSAIDs in patients with corneal epithelial breakdown
- Avoid administering while wearing contact lenses
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.