Doltro 10 mg (Tablet)

Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Unimed unihealth pharmaceuticals ltd
Also available as
Doltro 30 mg injection Doltro 60 mg injection

Indications

  • Short-term management of post-operative pain
  • Relief of pain after ocular surgery
  • Decrease in eye inflammation caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of NSAID
  • Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid and 2 - amino-2-(hydroxymethyl)-1,3-propanediol
  • Inhibits synthesis of prostaglandins
  • Metabolized in the liver
  • Excreted in the urine

Pharmacology

  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Recommended tablet dose: 10 mg every 4-6 hours
  • Recommended injection dose: varies by age and condition
  • Recommended eye drops dose: 1 drop in each eye 4 times daily

Interaction

  • Increased side effects with other NSAIDs or aspirin
  • Enhanced anti-coagulant effect with anti-coagulants
  • Reduced anti-hypertensive effect with beta blockers
  • Increased risk of renal impairment with ACE inhibitors
  • Enhanced toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Age restriction: Not for children under 16 years
  • Not to be used as prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Peptic ulcer
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • Pregnancy category: C
  • Avoid during pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
  • Discontinue use in case of corneal epithelial breakdown for ocular solution
  • Avoid use while wearing contact lenses for ocular solution

Therapeutic Class

  • Rheumatoid Arthritis medications
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of reach of children

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