Surgidol 10 mg (Tablet)
Unit Price: ৳ 45.00 (30's pack: ৳ 1,350.00)
Medicine Details
Category | Details |
---|---|
Generic | Ketorolac tromethamine |
Company | Globex pharmaceuticals ltd |
Also available as |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Description
- Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
- Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
- Inhibits synthesis of prostaglandins
- Pharmacokinetic property is linear
- Highly protein bound
- Mostly metabolized in the liver
Pharmacology
- Potent analgesic
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours, short-term use up to 7 days
- Injection recommended doses based on age, weight, and renal function
- Eye drops: 1 drop in each eye 4 times daily
Interaction
- Other NSAIDs or aspirin: Increase side effects
- Anti-coagulants: Enhance anti-coagulant effect
- Beta Blocker: Reduce anti-hypertensive effect
- ACE Inhibitors: Increase risk of renal impairment
- Methotrexate: Enhance toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melana
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category: C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over the age of 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use of topical NSAIDs in case of corneal epithelial breakdown
- Avoid administration while wearing contact lenses
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children