Dominat 10 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Nipa pharmaceuticals ltd |
| Also available as |
Title and Categories
- Dominat 10 mg Tablet
- Medication
- Gastrointestinal Drugs
Description
- Dopamine Antagonist Medication
- Treatment for nausea and vomiting
- Relieves dyspeptic symptoms
- Pharmacological action in the Chemoreceptor Trigger Zone and stomach
- Enhances gastric emptying and gastrointestinal motility
- Regulates contraction of the pylorus
- Increases esophageal peristalsis and lower esophageal sphincter pressure
- Restores normal motility and tone of the upper gastrointestinal tract
- Prevents regurgitation of gastric content
Dosage and Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
- Maximum dose for adults: 80 mg daily
- Recommended doses for children based on body weight
- By rectum in suppositories for adults and children
- Specific dosage for dyspeptic symptoms and acute nausea and vomiting
Interaction
- Concomitant administration of anticholinergic drugs
- Effects of antacids and antisecretory drugs on bioavailability
- Metabolic pathway through CYP3A4
- Inhibition of CYP3A4 by certain drugs
- Interaction with neuroleptics and dopaminergic agonists
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Conditions where gastrointestinal stimulation might be dangerous
- Prolactin-releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena in adults
- Increase in plasma prolactin level
- Possible neuroendocrinological phenomena
- Rare allergic reactions
Pregnancy & Lactation
- Limited use during the first trimester of pregnancy
- Excretion in breast milk
- Lower concentrations in breast milk compared to plasma
- Effects on ability to drive and use machines
Precautions & Warnings
- Absolute caution in children
- Increased risk of extrapyramidal reactions in young children
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Use in infants with caution and close medical supervision
- Use with caution in patients with liver disorders
- Adjustment of dosing frequency in severe renal insufficiency
Overdose Effects
- Drowsiness, disorientation, and extrapyramidal reactions
- Recommendations for management of overdosage
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic Drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Use of Dominat 10 mg Tablet
- Quick Tips for taking Dominat 10 mg Tablet