Kepronol 0.5% (Ophthalmic Solution)
5 ml drop: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Monicopharma ltd |
| Also available as |
Title
- Kepronol
Categories
- Pain Management
- Ophthalmic Solution
- NSAID
- Analgesic
- Anti-inflammatory Drug
- Therapeutic Drug
Description
- Indicated for short-term management of moderate to severe acute post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
- Belongs to the pyrrolo-pyrrole group of NSAIDs
- Inhibits prostaglandin synthesis
- Highly protein bound
- Metabolized in the liver
- Excreted in the urine
- Minimal anti-inflammatory effect at its analgesic dose
Dosage & Administration
- Tablet form: Recommended dose of 10 mg every 4-6 hours for up to 7 days
- Injection form: Single or multiple doses for postoperative pain management
- Eye Drops: 1 drop in each eye 4 times daily
- Specific dosages based on age, renal function, and body weight
- Maximum daily doses for different patient populations
- Single-dose and multiple-dose treatment guidelines
- Conversion from parenteral to oral therapy
- Maximum duration of combined parenteral and oral treatment is 5 days
Mode of Action
- Inhibits cyclooxygenase enzyme system
- Demonstrates minimal anti-inflammatory effect at analgesic dose
Interactions
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Age under 16 years
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- US FDA pregnancy category - C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with active/suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Eye Drops: Discontinue if corneal epithelial breakdown occurs
- Avoid administering while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis Medications
- Non-Opioid Analgesics
Storage Conditions
- Store in a dry place away from light and heat
- Keep out of the reach of children