Dominat 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 27.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Nipa pharmaceuticals ltd
Also available as
Dominat 10 mg tablet

Product Title

  • Dominat 5 mg/5 ml Suspension

Pharmacological Class

  • Dopamine antagonist
  • Prokinetic drug
  • Motility stimulant

Therapeutic Use

  • Treatment of dyspeptic symptom complex
  • Acute nausea and vomiting
  • Parkinson's disease-induced nausea and vomiting
  • Speeding barium transit in radiological studies

Dosage Form

  • Oral suspension

Active Ingredient

  • Domperidone

Dosage Instructions

  • Adults: 10-20 mg (1-2 tablet or 10-20 ml suspension), every 6-8 hours daily
  • Children: Dosage based on body weight, every 6-8 hours daily

Administration Time

  • 15-30 minutes before meals and at bedtime if necessary

Maximum Daily Dose

  • 80 mg for adults

Route of Administration

  • Oral
  • Rectal (suppositories)

Drug Interaction

  • Concomitant use of anticholinergic drugs may antagonize the effects
  • Simultaneous use with antacids and antisecretory drugs lowers bioavailability

Metabolism

  • Mainly through CYP3A4 pathway

Common Adverse Effects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Allergic reactions such as rash and urticaria

Contraindications

  • Hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage, obstruction, or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

Pregnancy and Lactation

  • Use in the first trimester justified by therapeutic benefit
  • Not recommended during breastfeeding unless benefits outweigh risks

Special Populations

  • Use in infants with caution and close medical supervision
  • Caution in patients with hepatic impairment
  • Dosing adjustment in severe renal insufficiency

Overdose Symptoms

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions especially in children

Storage Conditions

  • Store below 30°C, protected from light and moisture, keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2

Common Questions

  • What is Dominat 5 mg/5 ml Suspension used for?
  • Quick Tips for taking Dominat 5 mg/5 ml Suspension

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