Toroaid 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 80.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company General pharmaceuticals ltd
Also available as
Toroaid 10 mg tablet Toroaid 30 mg injection Toroaid 60 mg injection

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relieves pain, inflammation, and light sensitivity after ocular surgery
  • Decreases eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Chemically known as 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins
  • Biological activity associated with the S-form
  • Highly protein bound and largely metabolized in the liver

Pharmacology

  • Potent analgesic non-steroidal anti-inflammatory drug (NSAID)
  • Inhibits the cyclooxygenase enzyme system and prostaglandin synthesis

Dosage & Administration

  • Tablet recommended dose: 10 mg every 4-6 hours
  • Injection recommended dose: varies based on age and condition
  • Eye Drops: Adults - 1 drop in each eye 4 times daily

Interaction

  • Increases side effects with other NSAIDs or aspirin
  • Enhances anti-coagulant effect with anti-coagulants
  • Reduces anti-hypertensive effect with Beta Blockers
  • Increases risk of renal impairment with ACE Inhibitors
  • Enhances toxicity of methotrexate

Contraindications

  • Hypersensitivity to ketorolac or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • FDA Pregnancy category: C
  • Avoid in pregnancy and lactation unless benefits outweigh risks to fetus

Precautions & Warnings

  • Exercise caution in patients over 65 years
  • Active or suspected peptic ulcer or gastrointestinal bleeding
  • Asthma and liver dysfunction
  • Avoid in patients with evidence of corneal epithelial breakdown
  • Avoid administration while wearing contact lenses

Therapeutic Class

  • Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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