Domiren 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Renata limited |
| Also available as |
Title
- Domiren 5 mg/5 ml Suspension
Categories
- Medicine
- Pharmaceuticals
- Healthcare
- Treatment
Description
- Dopamine antagonist medication
- Relieves nausea and vomiting
- Used for dyspeptic symptom complex
- Acute nausea and vomiting
- Treatment for Parkinson's disease
- Speeds barium transit in radiological studies
- Pregnancy and lactation precautions
Dimensions
- 5 mg/5 ml
Color Options
- Clear liquid
Functions
- Relief of dyspeptic symptoms
- Promotes gastric emptying
- Enhances gastrointestinal motility
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Restores normal upper gastrointestinal tract motility
Materials
- Domperidone
Technical Specifications
- Oral dose for adults: 10-20 mg (1-2 tablets or 10-20 ml suspension) every 6-8 hours
- Oral dose for children: 2-4 ml suspension/10 kg body weight or 0.4-0.8 ml pediatric drops/10 kg body weight every 6-8 hours
- Maximum daily dose: 80 mg
- Rectal dose for adults: 30-60 mg every 4-8 hours
- Rectal dose for children: Up to 30 mg for those weighing 10 to 25 kg
Design Elements
- Suspension formulation
- Suppositories
- Packaging
Usability Features
- Precautions for children and patients with hepatic impairment
Dosage and Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
Interaction
- Antagonism with anticholinergic drugs
- Lower oral bioavailability with antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Possible influence on absorption of concomitantly orally administered drugs
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions
Pregnancy and Lactation
- Use in the first trimester if justified by therapeutic benefit
- Excretion in breast milk
- Caution for nursing mothers
Precautions and Warnings
- Use with caution in children due to risk of extra-pyramidal reactions
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants
- Caution in liver disorders
- Renal insufficiency considerations
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
- Administration of activated charcoal is recommended
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
Commonly Asked Questions
- Indications of use
- Quick tips for usage