G-Neostigmine 0.5 mg/ml (Injection)
1 ml ampoule: ৳ 10.00 (1 x 5: ৳ 50.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Neostigmine methylsulphate |
| Company | Gonoshasthaya pharma ltd |
Indications
- The symptomatic control of myasthenia gravis
- Prevention and treatment of postoperative distention
- Urinary retention after mechanical obstruction exclusion
- Reversal of effects of nondepolarizing neuromuscular blocking agents
Pharmacology
- Parasympathomimetic action
- Reversible cholinesterase inhibitor
- Stimulates nicotinic and muscarinic receptors
- Does not cross the blood-brain barrier
Dosage & Administration
- Dosage for adults
- Dosage for children
- Dosage for myasthenia gravis
- Dosage for urinary retention
- Duration of action
- Recommended ratio of atropine to neostigmine methylsulfate
Interaction
- Interactions with muscle relaxants
- Antibiotic interactions
- Interactions with anesthetics
- Interactions with antiarrhythmic agents
Contraindications
- Known hypersensitivity
- Peritonitis
- Mechanical obstruction of intestinal or urinary tract
Side Effects
- Cardiovascular adverse reactions
- Central nervous system adverse reactions
- Gastrointestinal adverse reactions
- Genitourinary adverse reactions
- Musculoskeletal adverse reactions
- Respiratory adverse reactions
- Allergic reactions
- Skin reactions
Pregnancy & Lactation
- Pregnancy category
- Nonteratogenic effects
- Use in lactation
Precautions & Warnings
- Use with caution in patients with epilepsy
- Caution in patients with bronchial asthma
- Caution in patients with bradycardia
- Caution in patients with recent coronary occlusion
Overdose Effects
- Cholinergic crisis
- Myasthenic crisis
- Respiratory paralysis
- Differentiation between crises
Therapeutic Class
- Anti-cholinesterases
- Drugs used in Myasthenia Gravis
Storage Conditions
- Controlled room temperature
- Protection from light
- Discard remaining contents