Neos-R 0.5 mg/ml (Injection)
1 ml ampoule: ৳ 8.00 (1 x 5: ৳ 40.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Neostigmine methylsulphate |
| Company | Renata limited |
Indications
- Symptomatic control of myasthenia gravis
- Prevention of postoperative distention
- Treatment of urinary retention
- Reversal of effects of nondepolarizing neuromuscular blocking agents
Pharmacology
- Sterile solution for intramuscular, intravenous, or subcutaneous administration
- Parasympathomimetic
- Reversible cholinesterase inhibitor
- Stimulates nicotinic and muscarinic receptors
Dosage & Administration
- Adult dosage
- Children dosage
- Duration of action
- Prophylactic dosage
- Treatment dosage
Interactions
- Prolongs Phase I block of depolarizing muscle relaxants
- Potential interaction with antibiotics and anesthetics
- Careful adjustment with certain antibiotics
- Cautious use with other drugs affecting neuromuscular transmission
Contraindications
- Known hypersensitivity
- Peritonitis
- Mechanical obstruction of intestinal or urinary tract
Side Effects
- Cardiovascular adverse reactions
- Central nervous system adverse reactions
- Gastrointestinal adverse reactions
- Genitourinary adverse reactions
- Musculoskeletal adverse reactions
- Respiratory adverse reactions
- Allergic reactions
- Skin reactions
Pregnancy & Lactation
- Pregnancy category C
- Potential uterine irritability
- Uncertain excretion in human milk
- Consideration for nursing mothers
Precautions & Warnings
- Caution in patients with specific conditions
- Potential need for atropine sulfate
- Separate syringes for atropine and the medication
Overdose Effects
- Cholinergic crisis
- Myasthenic crisis
- Respiratory paralysis
- Differentiation from cholinergic crisis
Therapeutic Class
- Anti-cholinesterases
- Drugs used in Myasthenia Gravis
Storage Conditions
- Controlled room temperature
- Protection from light
- Discarding remaining contents