Anespine 0.5%+8% (Intraspinal Injection)

Indications

• Lower abdominal surgery
• Caesarean section
• Urological surgery
• Lower limb surgery
• Hip surgery
• Intrathecal anesthesia
• Surgical procedures
• Obstetrical procedures
• Motor blockade
• Analgesia

Composition

• Bupivacaine Hydrochloride USP 20 mg
• Dextrose Anhydrous USP 320 mg

Pharmacology

• Long acting local anesthetic
• Amide type anesthetic
• Rapid onset of action
• Duration of analgesia
• Muscular relaxation
• Circulatory effects
• Tissue tolerance

Dosage & administration

• Spinal anesthesia dosage
• Pediatric dosage
• Patient's physical status consideration
• Concomitant medication consideration

Interaction

• Careful use with antiarrhythmic drugs
• Potential additive toxic effects

Contraindications

• Allergy or hypersensitivity to amide type local anesthetics
• Acute active diseases of the cerebrospinal system
• Spinal stenosis and active disease or recent trauma in the vertebral column
• Relative contraindications

Side effects

• Adverse reactions profile
• Physiological effects
• Nerve trauma
• Cerebrospinal leakage

Pregnancy & lactation

• No specific disturbances to reproductive process
• Dose reduction in late stages of pregnancy
• Excretion in breast milk

Precautions & warnings

• Reactivity with metals
• Single use ampoules
• Immediate use after opening
• Discard discolored solutions

Overdose effects

• Acute emergencies
• High plasma levels
• Delay in toxic signs
• Central nervous system effects
• Cardiovascular effects

Therapeutic class

• Regional anesthesia

Storage conditions

• Temperature not exceeding 30°C
• Dry place
• Protection from light

Related Brands