Anespine 0.5%+8% (Intraspinal Injection)

4 ml ampoule: ৳ 30.20 (5 x 2: ৳ 302.00)

Medicine Details

Category Details
Generic Bupivacaine hydrochloride dextrose
Company Square pharmaceuticals plc

Indications

  • Lower abdominal surgery
  • Caesarean section
  • Urological surgery
  • Lower limb surgery
  • Hip surgery
  • Intrathecal anesthesia
  • Surgical procedures
  • Obstetrical procedures
  • Motor blockade
  • Analgesia

Composition

  • Bupivacaine Hydrochloride USP 20 mg
  • Dextrose Anhydrous USP 320 mg

Pharmacology

  • Long acting local anesthetic
  • Amide type anesthetic
  • Rapid onset of action
  • Duration of analgesia
  • Muscular relaxation
  • Circulatory effects
  • Tissue tolerance

Dosage & administration

  • Spinal anesthesia dosage
  • Pediatric dosage
  • Patient's physical status consideration
  • Concomitant medication consideration

Interaction

  • Careful use with antiarrhythmic drugs
  • Potential additive toxic effects

Contraindications

  • Allergy or hypersensitivity to amide type local anesthetics
  • Acute active diseases of the cerebrospinal system
  • Spinal stenosis and active disease or recent trauma in the vertebral column
  • Relative contraindications

Side effects

  • Adverse reactions profile
  • Physiological effects
  • Nerve trauma
  • Cerebrospinal leakage

Pregnancy & lactation

  • No specific disturbances to reproductive process
  • Dose reduction in late stages of pregnancy
  • Excretion in breast milk

Precautions & warnings

  • Reactivity with metals
  • Single use ampoules
  • Immediate use after opening
  • Discard discolored solutions

Overdose effects

  • Acute emergencies
  • High plasma levels
  • Delay in toxic signs
  • Central nervous system effects
  • Cardiovascular effects

Therapeutic class

  • Regional anesthesia

Storage conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light

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