Bupicain Heavy 0.5%+8% (Intraspinal Injection)

4 ml ampoule: ৳ 28.00 (2 x 5: ৳ 280.00)

Medicine Details

Category Details
Generic Bupivacaine hydrochloride dextrose
Company Chemist laboratories ltd

Indications

  • Lower abdominal surgery
  • Caesarean section
  • Urological surgery
  • Lower limb surgery
  • Hip surgery
  • Intrathecal anesthesia
  • Surgical procedures
  • Obstetrical procedures
  • Motor blockade
  • Analgesia

Composition

  • Bupivacaine Hydrochloride USP 20 mg
  • Dextrose Anhydrous USP 320 mg

Pharmacology

  • Long acting local anesthetic
  • Amide type
  • Rapid onset of action
  • Duration of analgesia
  • Muscular relaxation
  • Circulatory effects
  • Tissue tolerance

Dosage & Administration

  • Spinal anesthesia dose for surgery
  • Pediatric dosage
  • Physical status consideration
  • Concomitant medication consideration
  • Elderly patient dose adjustment
  • Dose reduction in late pregnancy
  • CSF volume differences in children

Interaction

  • Use with antiarrhythmic drugs
  • Additive toxic effects
  • Phenothiazines and Butyrophenones interaction with epinephrine

Contraindications

  • Allergy or hypersensitivity to amide type local anesthetics
  • Diseases of the cerebrospinal system
  • Spinal stenosis
  • Diseases of the vertebral column

Side Effects

  • Adverse reactions
  • Physiological effects of nerve block
  • Nerve trauma
  • Epidural abscess
  • Cerebrospinal leakage

Pregnancy & Lactation

  • No specific disturbances reported
  • Dose reduction in late pregnancy
  • Negligible transfer to breast milk

Precautions & Warnings

  • Reactivity with metals
  • Single-use ampoules
  • Immediate use after opening
  • Discard discolored solutions

Overdose Effects

  • High plasma levels
  • Acute systemic toxicity
  • Delay in toxic signs
  • Central nervous system toxicity
  • Cardiovascular system toxicity

Therapeutic Class

  • Regional anesthesia

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light

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