Bupi Heavy 0.5%+8% (Intraspinal Injection)

4 ml ampoule: ৳ 30.11 (1 x 5: ৳ 150.56)

Medicine Details

Indications

  • Lower abdominal surgery
  • Caesarean section
  • Urological surgery
  • Lower limb surgery
  • Hip surgery
  • Intrathecal anesthesia
  • Surgical procedures
  • Obstetrical procedures
  • Motor blockade
  • Duration of analgesia

Composition

  • Bupivacaine Hydrochloride USP 20 mg
  • Dextrose Anhydrous USP 320 mg

Pharmacology

  • Long-acting local anesthetic
  • Amide type
  • Sterile non-glucose containing solution
  • Rapid onset of action
  • Duration of analgesia
  • Muscular relaxation
  • Circulatory effects
  • Tissue tolerance

Dosage and administration

  • Spinal anesthesia dosage
  • Average adult dosage
  • Pediatric dosage
  • Physical status consideration
  • Concomitant medication consideration
  • Segmental spread variation
  • Dose reduction in elderly
  • Dose reduction in late pregnancy
  • Dose/kg variation in children

Interaction

  • Use with antiarrhythmic drugs
  • Toxic effects
  • Pressor effect reversal

Contraindications

  • Allergy to amide type local anesthetics
  • Active cerebrospinal diseases
  • Spinal stenosis
  • Vertebral column diseases

Side effects

  • Adverse reaction profile
  • Decrease in blood pressure
  • Bradycardia
  • Temporary urinary retention
  • Nerve trauma
  • Epidural abscess
  • Cerebrospinal leakage

Pregnancy and lactation

  • Use during pregnancy
  • Use during lactation
  • Dose adjustment in late pregnancy
  • Breast milk concentration

Precautions and warnings

  • Reaction with metals
  • Irritation potential
  • Single use ampoules
  • Solution discard
  • Immediate use
  • Discoloration indication

Overdose effects

  • Acute emergencies
  • High plasma levels
  • Toxicity
  • Intravascular injections
  • Peak plasma concentrations
  • Delayed toxic signs

Therapeutic class

  • Regional anesthesia

Storage conditions

  • Temperature limit
  • Dry place storage
  • Light protection

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