Duracain 0.5%+8% (Intraspinal Injection)

4 ml ampoule: ৳ 30.00 (1 x 5: ৳ 150.00)

Medicine Details

Category Details
Generic Bupivacaine hydrochloride dextrose
Company Techno drugs ltd

Indications

  • Lower abdominal surgery
  • Caesarean section
  • Urological surgery
  • Lower limb surgery
  • Hip surgery
  • Intrathecal anesthesia
  • Surgical procedures
  • Obstetrical procedures
  • Motor blockade
  • Analgesia

Composition

  • Bupivacaine Hydrochloride USP 20 mg
  • Dextrose Anhydrous USP 320 mg

Pharmacology

  • Long acting local anesthetic
  • Amide type
  • Rapid onset of action
  • Duration of analgesia
  • Muscular relaxation
  • Profound lower limb relaxation
  • Circulatory effects
  • Tissue tolerance

Dosage & Administration

  • Spinal anesthesia dosage
  • Pediatric dosage
  • Physical status consideration
  • Concomitant medication consideration
  • Dose adjustment for elderly
  • Dose adjustment for late pregnancy
  • Dose adjustment for children

Interaction

  • Antiarrhythmic drug interaction
  • Additive toxic effects

Contraindications

  • Allergy or hypersensitivity
  • Active diseases of cerebrospinal system
  • Spinal stenosis
  • Arthritis
  • Diseases of vertebral column

Side Effects

  • Adverse reaction profile
  • Decrease in blood pressure
  • Bradycardia
  • Urinary retention
  • Nerve trauma
  • Epidural abscess
  • Cerebrospinal leakage

Pregnancy & Lactation

  • Safety in pregnancy
  • Dose adjustment in late pregnancy
  • Breastfeeding safety

Precautions & Warnings

  • Reactivity with metals
  • Single use only
  • Immediate use
  • Discard discolored solutions

Overdose Effects

  • Acute emergencies
  • High plasma levels
  • Systemic toxicity
  • Intravascular injections
  • Peak plasma concentrations
  • Toxic reactions
  • Delayed toxic signs

Therapeutic Class

  • Regional anesthesia

Storage Conditions

  • Temperature limits
  • Dry place
  • Protection from light

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