Dompi 10 mg (Tablet)
Unit Price: ৳ 2.50 (16 x 10: ৳ 400.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Alco pharma ltd |
| Also available as |
Manufacturer and Brand
- Manufacturer: Generic
- Brand: Dompi 10 mg Tablet
Categories
- Medicine
- Gastrointestinal Health
- Nausea & Vomiting Relief
Dosage Form
Tablet, Suspension, Pediatric Drops, Suppository
Dosage Strength
10 mg
Color Options
- White
Dimensions
Standard tablet size
Indications
- Dyspeptic Symptom Complex
- Delayed Gastric Emptying
- Gastroesophageal Reflux
- Esophagitis
- Non-ulcer Dyspepsia
- Acute Nausea
- Acute Vomiting
- Parkinson's Disease
- Radiological Studies
Pharmacological Action
Dopamine Antagonist, Gastroprokinetic
Mode of Action
Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach, restores normal motility and tone of upper GI tract
Gastrointestinal Effects
- Facilitates Gastric Emptying
- Enhances Antral and Duodenal Peristalsis
- Regulates Contraction of the Pylorus
- Increases Esophageal Peristalsis
- Regulates Lower Esophageal Sphincter Pressure
Usability
- Taken before meals and bedtime
- Relieves Nausea, Vomiting, Indigestion
Dosage Recommendations
- Adults: 10-20 mg, every 6-8 hours daily
- Children: 2-4 ml suspension/10 kg body weight, every 6-8 hours daily
Maximum Daily Dose
80 mg
Interaction
- Contraindicated with anticholinergic drugs
- Simultaneous use with antacids and antisecretory drugs lowers oral bioavailability
- Metabolized through CYP3A4 pathway
Contraindications
- Known hypersensitivity
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
- Rare allergic reactions (rash, urticaria)
Pregnancy & Lactation
Use during first trimester justified by therapeutic benefit
Excretion in Breast Milk
4 times lower than plasma concentrations
Precautions
- Use with caution in children due to risk of extra-pyramidal reactions
- Use with caution in hepatic impairment
Special Populations
- Infants: Caution and medical supervision
- Liver Disorders: Caution
- Kidney Disorders: Dosing adjustment based on severity
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
Therapeutic Class
- Motility Stimulants
- Dopamine Antagonist
- Prokinetic Drugs
Storage Conditions
Store below 30°C, Protected from light & moisture