Naligram 300 mg/5 ml (Oral Suspension)

50 ml bottle: ৳ 43.13

Medicine Details

Category Details
Generic Nalidixic acid
Company Acme laboratories ltd
Also available as
Naligram 500 mg tablet

Indications

  • Urinary tract infection treatment
  • Gram-negative organisms
  • Proteus species
  • Klebsiella species
  • Enterobacter species
  • Escherichia coli

Pharmacology

  • Narrow spectrum antibacterial
  • Bacteriostatic
  • Bactericidal
  • Inhibition of bacterial DNA synthesis
  • DNA polymerization interference
  • Absorption from G.I. tract
  • Tissue distribution
  • Excretion rate

Dosage & Administration

  • Adult dosage
  • Children dosage
  • Initial dosing
  • Maintenance dosing

Interaction

  • Concomitant use with melphalan
  • Reports of severe blood containing diarrhoea
  • Concomitant use with probenecid
  • Elevation of serum concentration
  • Concomitant use with chlorpromazine
  • Potentiation effect with Perphenazine

Contraindications

  • Infants under 3 months
  • Epilepsy
  • CNS lesions

Side Effects

  • Gastro-intestinal disturbances
  • Nausea
  • Vomiting
  • Diarrhoea
  • Haemolysis in G6PD deficiency
  • Allergic reactions
  • Urticaria
  • Rashes
  • Fever
  • Arthralgia
  • Eosinophilia
  • Myalgia
  • Muscle weakness
  • Phototoxicity
  • Jaundice
  • Visual disturbances
  • Convulsions

Pregnancy & Lactation

  • Cartilage damage possibility
  • DNA damage possibility
  • Excretion in breast milk
  • Risk during breast feeding
  • Hemolytic anaemia in breastfed child

Precautions & Warnings

  • Risk-benefit considerations
  • First trimester of pregnancy
  • Impaired renal function
  • Impaired hepatic function

Therapeutic Class

  • Anti-diarrhoeal
  • Antimicrobial drugs
  • Anti-protozoals
  • Systemic Urinary Anti-infective

Storage Conditions

  • Temperature conditions
  • Protection from light and moisture
  • Keep out of reach of children

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