Nintoin 25 mg/5 ml (Oral Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Nitrofurantoin
Company Incepta pharmaceuticals ltd
Also available as
Nintoin 100 mg tablet Nintoin sr 100 mg capsule Nintoin 50 mg capsule

Indications

  • Treatment of urinary tract infections
  • Prophylaxis of urinary tract infections
  • Target bacteria: Escherichia coli
  • Target bacteria: Enterococci
  • Target bacteria: Staphylococcus aureus
  • Target bacteria: Staphylococcus saprophyticus
  • Target bacteria: Klebsiella species
  • Target bacteria: Enterobacter species

Pharmacology

  • Specific for urinary tract infections
  • Highly soluble in urine
  • Inactivation of bacterial ribosomal proteins
  • Activity against Gram-Positive Aerobes
  • Activity against Gram-Negative Aerobes

Dosage

  • Dosage for uncomplicated urinary tract infections in adults
  • Dosage for long-term suppressive therapy in adults
  • Dosage for acute uncomplicated urinary tract infections in adults
  • Dosage for long term suppression in adults
  • Dosage for prophylaxis in adults
  • Dosage for genito-urinary surgical prophylaxis in adults
  • Dosage for pediatric patients
  • Average doses for pediatric patients based on weight

Administration

  • Should be taken with food

Interaction

  • Interaction with antacids containing Magnesium Trisilicate
  • Interaction with uricosuric drugs like Probenecid and Sulfinpyrazone

Contraindications

  • Contraindicated in anuria, oliguria, or significant impairment of renal function
  • Contraindicated in pregnant patients at 38-42 weeks, during labor and delivery
  • Contraindicated in patients with known hypersensitivity to Nitrofurantoin

Side Effects

  • Frequent adverse events: nausea, headache, flatulence
  • Less frequent adverse events: diarrhea, dyspepsia, abdominal pain, constipation, emesis, dizziness, drowsiness

Pregnancy & Lactation

  • Pregnancy Category B
  • Limited data on usage during pregnancy
  • Detection in human breast milk in trace amounts
  • Consideration for nursing infants under one month of age

Precautions & Warnings

  • Discontinuation if pulmonary reactions occur
  • Avoidance of antacid preparations containing magnesium trisilicate

Overdose Effects

  • Occasional incidents of vomiting in acute overdosage
  • Induction of emesis recommended

Therapeutic Class

  • Systemic Urinary Anti-infective

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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