Urocure 25 mg/5 ml (Oral Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category	Details
Generic	Nitrofurantoin
Company	Square pharmaceuticals plc
Also available as	Urocure sr 100 mg capsule

Indications

Treatment of urinary tract infections
Prophylaxis of urinary tract infections
Targeted bacterial strains - Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus, Klebsiella, Enterobacter

Pharmacology

Nitrofurantoin is specific for urinary tract infections
High solubility in urine
Inactivates or alters bacterial ribosomal proteins
Activity against Gram-Positive Aerobes and Gram-Negative Aerobes

Dosage

Different dosages for adults and children
Recommendations for uncomplicated urinary tract infections
Dosage adjustment for long-term suppressive therapy

Administration

Should be taken with food

Interaction

Reduction of absorption with Antacids containing Magnesium Trisilicate
Inhibition of renal tubular secretion by Uricosuric drugs

Contraindications

Anuria, oliguria, or significant impairment of renal function
Pregnant patients at 38-42 weeks, during labor and delivery
Known hypersensitivity to Nitrofurantoin

Side Effects

Frequent adverse events - nausea, headache, flatulence
Less occurred adverse events - diarrhea, dyspepsia, abdominal pain, constipation, emesis, dizziness, drowsiness

Pregnancy & Lactation

Pregnancy Category B
No adequate and well-controlled studies in pregnant women
Detection in human breast milk
Need to consider drug importance for nursing mother

Precautions & Warnings

Discontinue if acute, sub-acute, or chronic pulmonary reactions occur
Avoid antacid preparations containing magnesium trisilicate

Overdose Effects

Occasional incidents of acute overdosage
Induction of emesis recommended

Therapeutic Class

Systemic Urinary Anti-infective

Storage Conditions

Do not store above 30°C
Keep away from light
Keep out of the reach of children

Related Brands