Uriset (1500 mg+250 mg)/5 ml (Oral Solution)
Medicine Details
| Category | Details |
|---|---|
| Generic | Potassium citrate citric acid |
| Company | Square pharmaceuticals plc |
Indications
- Relief of discomfort in urinary tract infections
- Prevention of kidney stones
- Prevention of gout with uricosuric agent
- Treatment of acidosis caused by kidney diseases
Pharmacology
Potassium Citrate and Citric Acid oral solution acts as a systemic alkalizer by metabolizing to Potassium Bicarbonate and alkalinizing the urine without causing systemic alkalosis. It is palatable and tolerable, suitable for long-term use.
Dosage & Administration
- Relief of discomfort in UTI:
- Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water
- Children 1-6 years: 5 ml 3 times daily, diluted with ½ glass of water
- Prevention of kidney stones, gout prevention, acidosis treatment:
- Adults: 10-15 ml 4 times daily, diluted with 1 glass of water (or as directed by physician)
- Pediatric: 5-10 ml 4 times daily, diluted with ½ glass of water (or as directed by physician)
Interaction
Concurrent administration of potassium-containing medication, potassium-sparing diuretics, ACE inhibitors, or cardiac glycosides may lead to toxicity.
Contraindications
Severe renal impairment with oliguria or azotemia, untreated Addison's disease, acute dehydration, severe myocardial damage, hyperkalemia
Side Effects
Well tolerated when given in recommended doses, caution in patients with abnormal renal mechanisms to avoid hyperkalemia or alkalosis
Pregnancy & Lactation
No available information on use during pregnancy and lactation
Precautions & Warnings
Use with caution in patients with low urinary output, dilute adequately with water, take after meals, avoid large doses in presence of renal disease
Overdose Effects
Oral Potassium salts rarely cause serious hyperkalemia in persons with normal potassium excretion, treatment measures include elimination of potassium sources, intravenous dextrose and insulin, use of exchange resins, hemodialysis or peritoneal dialysis
Therapeutic Class
- Prevention of repeated kidney stone formation
- Urinary Alkalinizing Agent
Storage Conditions
Keep below 30°C away from light and moisture, keep out of reach of children