Domsil 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 28.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Silva pharmaceuticals ltd |
| Also available as |
Title
Domperidone 5mg/5ml Suspension
Categories
- Medicine
- Gastrointestinal
- Pharmacology
- Therapeutic Class
- Side Effects
- Pregnancy & Lactation
- Precautions & Warnings
- Overdose Effects
- Compound Summary
- Common Questions about Domsil 5 mg/5 ml Suspension
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Block dopamine receptors
- Gastroprokinetic action
- Restores normal motility
- Facilitates gastric emptying
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
- Dosage for dyspeptic symptoms
- Dosage for acute and sub-acute conditions
- Rectal administration for adults and children
- Maximum period of treatment is 12 weeks
Interaction
- Antagonizes with anticholinergic drugs
- Lower oral bioavailability with antacids and antisecretory drugs
- Affected by CYP3A4 inhibitors
- Does not potentiate neuroleptics
- Suppresses unwanted peripheral effects of dopaminergic agonists
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk
- Not recommended during nursing
Precautions & Warnings
- Caution in children due to increased risk of extrapyramidal reactions
- Caution in patients with hepatic impairment
Use in Special Populations
- Use in infants with caution and under close supervision
- Caution in liver disorders
- Caution in kidney disorders
- Review of patients on prolonged therapy
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Administration of activated charcoal recommended
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure available
Common Questions about Domsil 5 mg/5 ml Suspension
- Used for treating nausea and vomiting
- Relieves nausea, vomiting, and indigestion
- Dosage and duration as prescribed by the doctor
- May cause dizziness and sleepiness
- Avoid consuming alcohol
- Dry mouth may occur as a side effect
- Inform the doctor for persistent symptoms
- Consultation required for prolonged use