Tamfast 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.03 (3 x 10: ৳ 300.90)
Strip Price: ৳ 100.30

Medicine Details

Category Details
Generic Tamsulosin hydrochloride
Company Radiant pharmaceuticals ltd
Also available as
Mictrol 04 mg capsule

Title

Tamfast Hydrochloride Capsules

Categories

  • Medicine
  • Health & Personal Care
  • Men's Health

Description

Tamsulosin Hydrochloride capsules for the treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)

Color Options

  • White

Dosage Form

Capsule

Dosage Strengths

  • 0.4mg
  • 0.8mg

Dosage Instructions

  • Take 1 capsule daily after a meal at night
  • May increase to 2 capsules daily after 2 to 4 weeks if necessary

Administration Method

Oral, Swallow whole with a glass of water

Contraindications

  • Hypersensitivity to Tamsulosin hydrochloride
  • History of orthostatic hypotension
  • Severe hepatic insufficiency

Indications

  • Treatment of symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

  • Selective alpha1 adrenoceptor blocking agent
  • Relaxes smooth muscle in bladder neck and prostate
  • Improvement in urine flow rate
  • Reduction in symptoms of BPH

Absorption

Essentially complete (90%) following oral administration under fasting conditions

Time to Maximum Concentration

  • 4-5 hours under fasting conditions
  • 6-7 hours when administered with food

Plasma Protein Binding

94% to 99%

Metabolism

Extensively metabolized by cytochrome P450 enzymes in the liver

Elimination Half-life

  • 5-7 hours in plasma
  • Approximately 9-13 hours in healthy volunteers
  • 14-15 hours in the target population

Interactions

  • Concomitant use of other alfa1-adrenoceptor antagonists
  • No interactions observed with atenolol, enalapril, or nifedipine
  • Concurrent cimetidine may raise plasma levels, frusemide may lower plasma levels
  • No interactions at the level of hepatic metabolism with selected drugs
  • Diclofenac and warfarin may increase the elimination rate

Side Effects

  • Dizziness
  • Abnormal ejaculation
  • Headache
  • Asthenia
  • Postural hypotension
  • Palpitations

Pregnancy & Lactation

Not recommended for use during pregnancy and lactation

Precautions & Warnings

  • Rare transient postural symptoms may occur
  • Use in patients with micturition syncope is not advised
  • Effect on ability to drive and use machines is not fully studied

Overdose Effects

  • Acute hypotension likely to occur
  • Cardiovascular support should be given
  • Renal function monitoring and general supportive measures should be applied
  • Gastric lavage and activated charcoal may be administered in case of acute overdosage

Therapeutic Class

BPH/ Urinary retention/ Urinary incontinence

Storage Conditions

Store in a cool and dry place, below 30°C, protected from light

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