Prostacin 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Tamsulosin hydrochloride
Company Incepta pharmaceuticals ltd

Therapeutic Class

  • BPH/ Urinary retention/ Urinary incontinence

Indications

  • Treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

  • Selective alpha1 adrenoceptor blocking agent
  • Improvement in urine flow rate
  • Reduction in symptoms of BPH
  • Absorption of Tamsulosin hydrochloride capsule
  • Metabolized by cytochrome P 450 enzymes
  • Excretion in urine as unchanged form
  • Elimination half-life of Tamsulosin hydrochloride in plasma

Dosage & Administration

  • Tamsulosin Hydrochloride 0.4 mg daily
  • Tamsulosin Hydrochloride 0.8 mg once daily
  • Administration after meal at night
  • Swallow whole with a glass of water
  • Do not crunched or chewed

Interaction

  • Concurrent administration of other alfa1-adrenoceptor antagonists
  • No interactions with atenolol, enalapril, or nifedipine
  • Interactions with cimetidine and frusemide
  • No interactions at the level of hepatic metabolism
  • Increase in elimination rate with diclofenac and warfarin

Contraindications

  • Hypersensitivity to Tamsulosin hydrochloride
  • History of orthostatic hypotension
  • Severe hepatic insufficiency
  • Reduction in blood pressure can occur
  • Syncope can occur
  • Examination before therapy initiation

Side Effects

  • Dizziness
  • Abnormal ejaculation
  • Headache
  • Asthenia
  • Postural hypotension
  • Palpitations

Pregnancy & Lactation

  • Use not recommended

Precautions & Warnings

  • Transient postural symptoms may occur
  • Use in patients with micturition syncope not advised
  • Effects on ability to drive and use machines

Overdose Effects

  • Acute hypotension likely to occur
  • Cardiovascular support should be given
  • Renal function should be monitored
  • General supportive measures applied
  • Measures to impede absorption
  • Gastric lavage and activated charcoal administration

Storage Conditions

  • Store in a cool and dry place
  • Below 30°C
  • Protected from light

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