Tamsule SR 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.03 (2 x 10: ৳ 200.60)

Strip Price: ৳ 100.30

Medicine Details

Category	Details
Generic	Tamsulosin hydrochloride
Company	Sharif pharmaceuticals ltd

Indications

Treats functional symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

Selective alpha1 adrenoceptor blocking agent
Improves urine flow rate
Reduces symptoms of BPH
High plasma protein binding
Extensively metabolized by liver enzymes

Dosage & Administration

One capsule (0.4 mg) daily, to be taken after meal at night
Dose may be increased to 0.8 mg once daily after 2 to 4 weeks
Swallow whole with a glass of water
Should not be crunched or chewed

Interaction

Concurrent administration with other alfa1-adrenoceptor antagonists could lead to hypotensive effects
No interactions with atenolol, enalapril, or nifedipine
Cimetidine increases plasma levels, frusemide decreases
No interactions at the level of hepatic metabolism except with diclofenac and warfarin

Contraindications

Hypersensitivity to tamsulosin hydrochloride
History of orthostatic hypotension
Severe hepatic insufficiency
Potential for reduction in blood pressure and syncope
Caution in situations where injury could result
Examination to exclude other conditions before therapy initiation

Side Effects

Dizziness
Abnormal ejaculation
Headache
Asthenia
Postural hypotension
Palpitations

Pregnancy & Lactation

Not recommended for use during pregnancy and lactation

Precautions & Warnings

Rare transient postural symptoms
Use in patients with micturition syncope not advised
Dizziness can occur
No data available on effect on ability to drive or operate machines

Overdose Effects

Acute hypotension likely after overdosage
Cardiovascular support should be given
Volume expanders and vasopressors may be employed
Renal function should be monitored

Therapeutic Class

BPH/ Urinary retention/ Urinary incontinence

Storage Conditions

Store in a cool and dry place, below 30°C, protected from light

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