Urocap 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Tamsulosin hydrochloride
Company Ibn sina pharmaceuticals ltd

Indications

  • Treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

  • Selective alpha1 adrenoceptor blocking agent
  • Relaxes smooth muscle in the bladder neck and prostate
  • Improves urine flow rate
  • Reduces symptoms of BPH
  • Absorption of 90% under fasting conditions
  • Extensively metabolized by liver enzymes

Dosage & Administration

  • Tamsulosin Hydrochloride 0.4 mg daily
  • May be increased to 0.8 mg once daily after 2 to 4 weeks
  • Swallow whole with a glass of water
  • Should not be crunched or chewed

Interaction

  • Concurrent administration with other alfa1-adrenoceptor antagonists can lead to hypotensive effects
  • No interactions with atenolol, enalapril or nifedipine
  • Cimetidine may increase plasma levels, frusemide may decrease levels
  • No interactions at hepatic metabolism level with amitriptyline, salbutamol, etc.
  • Diclofenac and warfarin may increase elimination rate

Contraindications

  • Hypersensitivity to Tamsulosin hydrochloride
  • History of orthostatic hypotension
  • Severe hepatic insufficiency
  • Potential reduction in blood pressure leading to syncope
  • Caution in situations where injury could result
  • Examination to exclude other conditions before therapy initiation

Side Effects

  • Dizziness
  • Abnormal ejaculation
  • Headache
  • Asthenia
  • Postural hypotension
  • Palpitations

Pregnancy & Lactation

  • Not recommended for use

Precautions & Warnings

  • Rare transient postural symptoms may occur
  • Not advised in patients with micturition syncope
  • No data available on effects on ability to drive or operate machines
  • Patients should be aware of the potential for dizziness

Overdose Effects

  • Acute hypotension likely after overdosage
  • Cardiovascular support should be given
  • Renal function monitoring and general supportive measures suggested
  • Measures such as emesis, gastric lavage and activated charcoal may be taken

Therapeutic Class

  • BPH/Urinary retention/Urinary incontinence

Storage Conditions

  • Store in a cool and dry place below 30°C, protected from light

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