Ezipas 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.00 (20's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Tamsulosin hydrochloride
Company Leon pharmaceuticals ltd

Indications

  • Treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

  • Tamsulosin is a selective alpha1 adrenoceptor blocking agent
  • Causes relaxation of smooth muscle in bladder neck and prostate
  • Improvement in urine flow rate and reduction in BPH symptoms
  • Absorption is 90% complete following oral administration under fasting conditions
  • Extensively metabolized by cytochrome P 450 enzymes in the liver

Dosage & Administration

  • Tamsulosin Hydrochloride 0.4 mg daily, to be taken after meal at night
  • Dose may be increased to 0.8 mg once daily after 2 to 4 weeks if necessary
  • Capsule should be swallowed whole with a glass of water

Interaction

  • Concurrent administration with other alfa1-adrenoceptor antagonists could lead to hypotensive effects
  • No interactions seen with atenolol, enalapril, or nifedipine
  • Concomitant cimetidine may raise plasma levels, frusemide may decrease plasma levels
  • Diclofenac and warfarin may increase elimination rate

Contraindications

  • Hypersensitivity to Tamsulosin hydrochloride
  • History of orthostatic hypotension
  • Severe hepatic insufficiency
  • Caution in situations where injury could result from reduced blood pressure

Side Effects

  • Dizziness
  • Abnormal ejaculation
  • Headache, asthenia, postural hypotension, palpitations

Pregnancy & Lactation

  • Not recommended for use during pregnancy and lactation

Precautions & Warnings

  • Transient postural symptoms may occur after the first dose
  • Caution in patients with micturition syncope
  • Patients should be aware of potential dizziness

Overdose Effects

  • Acute hypotension likely after overdosage
  • Cardiovascular support may be necessary
  • Renal function should be monitored
  • Gastric lavage and activated charcoal may be used

Therapeutic Class

  • BPH/ Urinary retention/ Urinary incontinence

Storage Conditions

  • Store in a cool and dry place, below 30°C, protected from light

Related Brands