Dopadon 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 36.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Category
- Digestive Health
- Medication
- Pharmacology
Dosage & Administration
- To be taken 15-30 minutes before meals
- Maximum daily dose of 80 mg for adults
- Different doses for dyspeptic symptoms and acute conditions
- Rectal administration for adults and children
- Maximum period of treatment is 12 weeks for acute nausea and vomiting
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in the CTZ and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Increases esophageal peristalsis
Interaction
- Antagonizes with anticholinergic drugs
- Lower its bioavailability with antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Potential interaction with CYP3A4 inhibitors and orally administered drugs
- Does not potentiate the action of neuroleptics
- Suppresses the unwanted peripheral effects of dopaminergic agonists
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions like rash and urticaria
Pregnancy & Lactation
- Limited use during the first trimester of pregnancy
- Excretion in breast milk
- Not recommended for nursing mothers unless benefits outweigh risks
- No effect on mental alertness
Precautions & Warnings
- Increased risk of extrapyramidal reactions in young children
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Use with caution in infants
- Use with caution in liver disorders
- Minimal adjustment needed in patients with renal insufficiency
- Patients on prolonged therapy should be reviewed regularly
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Recommended treatment includes administration of activated charcoal and close observation of the patient
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure available (link provided)
Common Questions about Dopadon 5 mg/5 ml Suspension
- Used to treat nausea and vomiting
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
- Avoid consuming alcohol
- Inform doctor if watery diarrhea, fever, or stomach pain persists
- Do not take for longer than 7 days without consulting a doctor