Tamosin 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.00 (20's pack: ৳ 200.00)

Medicine Details

Indications

  • Treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

  • Selective alpha1 adrenoceptor blocking agent
  • Improvement in urine flow rate
  • Reduction in BPH symptoms
  • Complete absorption under fasting conditions
  • Extensive metabolism in the liver
  • High plasma protein binding
  • Elimination half-life in plasma

Dosage & Administration

  • 0.4 mg daily dosage
  • Increased dosage after 2 to 4 weeks if necessary
  • Instructions for administration with food
  • Swallowing capsule whole with water
  • Modified release of active ingredient

Interaction

  • Potential hypotensive effects with concurrent alpha1-adrenoceptor antagonists
  • No interactions with specific medications
  • Cimetidine and frusemide effects on plasma levels
  • No interactions at the level of hepatic metabolism
  • Effects of diclofenac and warfarin on Tamsulosin elimination

Contraindications

  • Hypersensitivity
  • History of orthostatic hypotension
  • Severe hepatic insufficiency
  • Possible reduction in blood pressure
  • Caution for orthostatic hypotension symptoms
  • Recommendation for patient examination before therapy initiation
  • Adverse effects on driving and operating machinery

Side Effects

  • Dizziness
  • Abnormal ejaculation
  • Headache
  • Asthenia
  • Postural hypotension
  • Palpitations

Pregnancy & Lactation

  • Not recommended for use

Precautions & Warnings

  • Transient postural symptoms after first dose
  • Not advised in patients with micturition syncope
  • Uncertain effects on ability to drive or operate machines
  • Patient awareness of potential dizziness

Overdose Effects

  • Likely acute hypotension after overdosage
  • Recommendations for cardiovascular support and monitoring
  • Binding to plasma proteins limiting dialysis effectiveness

Therapeutic Class

  • BPH/Urinary retention/Urinary incontinence

Storage Conditions

  • Cool and dry storage below 30°C
  • Protection from light

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