Flamyd 0.75% (Vaginal Gel)

30 gm tube: ৳ 50.00

Medicine Details

Title

Flamyd 0.75% Vaginal Gel

Categories

  • Medicine
  • Antibiotic
  • Antiprotozoal
  • Amoebicide

Description

Flamyd 0.75% Vaginal Gel is indicated for the treatment and prevention of various infections such as trichomoniasis, amoebiasis, bacterial vaginosis, giardiasis, acute ulcerative gingivitis, anaerobically infected leg ulcers, and more. It is also used in the prevention of post-operative infections due to anaerobic bacteria.

Indications

  • Prevention of post-operative infections due to anaerobic bacteria
  • Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis
  • Treatment of urogenital trichomoniasis
  • Treatment of bacterial vaginosis
  • Treatment of all forms of amoebiasis
  • Treatment of giardiasis
  • Treatment of acute ulcerative gingivitis
  • Treatment of anaerobically infected leg ulcers and pressure sores
  • Treatment of acute dental infections due to anaerobic organisms
  • Treatment of antibiotic associated pseudomembranous colitis

Pharmacology

  • Metronidazole is a member of the imidazole class of antibacterial drug
  • Classified therapeutically as an antiprotozoal agent
  • Chemically acts by interacting with DNA and giving bactericidal action

DosageAndAdministration

  • TabletAndSuspension:
    • Contains dosages for trichomoniasis in adults and children over 10 years
    • Contains dosages for various amoebiasis categories
    • Contains dosages for giardiasis and acute ulcerative gingivitis
    • Contains dosages for bacterial vaginosis, leg ulcers, anaerobic infections, and surgical prophylaxis
  • VaginalGel: Recommended dose is one applicator full intravaginally once or twice a day for 5 days
  • Suppository: Contains dosages for anaerobic infections and surgical prophylaxis
  • IVInfusion:
    • Contains dosages for adults and children over 12 years
    • Contains dosages for children under 12 years

Interaction

  • Interaction with disulfiram leading to psychotic reactions
  • Interaction with alcohol causing antabuse effect
  • Interaction with oral anticoagulant therapy
  • Interaction with lithium, cyclosporin, phenytoin/phenobarbital, 5-fluorouracil, and busulfan

Contraindications

Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives

SideEffects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

PregnancyAndLactation

US FDA Pregnancy Category B; caution should be exercised when administered to a nursing woman

PrecautionsAndWarnings

  • Monitoring hematological tests if administered longer than recommended duration
  • Administering with caution to patients with hepatic encephalopathy
  • Warning patients about darkening of urine

UseInSpecialPopulations

  • Dosage reduction in hepatic impairment
  • No routine adjustment in the dosage needed in patients with renal failure undergoing dialysis

OverdoseEffects

Reported symptoms include vomiting, ataxia, and slight disorientation; no specific antidote available

TherapeuticClass

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

StorageConditions

Store below 30°C, protected from light, and out of the reach of children

CommonlyAskedQuestions

  • Definition of Flamyd 0.75% Vaginal Gel
  • Uses of Flamyd 0.75% Vaginal Gel
  • Side effects of Flamyd 0.75% Vaginal Gel
  • Duration to see improvement
  • Contraindications
  • Safety during pregnancy
  • Effectiveness of higher than recommended dose

QuickTips

  • Treatment of infections caused by bacteria and parasites
  • May cause side effects like nausea, stomach upset, and metallic taste
  • Increased risk of side effects with high dose or prolonged use
  • Avoid alcohol consumption while on treatment
  • Inform doctor if having liver disease

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