Virux 200 mg/5 ml (Oral Suspension)
70 ml bottle: ৳ 125.85
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir oral |
| Company | Square pharmaceuticals plc |
| Also available as |
Title and Categories
- Aciclovir
- Antiviral Medication
- Herpes Simplex Virus Treatment
- Varicella Zoster Virus Treatment
Dimensions
- N/A
Color options
- N/A
Functions
- Treats viral infections caused by Herpes simplex virus (type I & II) and Varicella zoster virus
- Prophylaxis of Herpes simplex infections in immunocompromised patients
- Prevents recurrence of herpes simplex
- Prophylactic treatment of herpes simplex in immunocompromised patients
- Treats chicken pox (varicella)
- Treats herpes zoster (shingles)
- Treats initial rectal (proctitis) herpes infections
Materials
- Synthetic purine derivative
Technical Specifications
- Interferes with DNA synthesis and inhibits viral replication
- Converted to Aciclovir Triphosphate in infected cells
- 15-30% oral absorption from gastrointestinal tract
- Peak plasma concentrations within 1.5-2 hours after oral administration
- Widely distributed into body tissues and fluids including the brain, saliva, lungs, liver, muscle, spleen, uterus, vaginal mucosa, and secretions, cerebrospinal fluid, and herpetic vesicular fluid
- Excreted through the kidney by glomerular filtration & tubular secretion
Design Elements
- N/A
Usability Features
- Dosage adjustments for patients with renal impairment
- Store below 25°C
- Protected from light and moisture
- Keep out of reach of children
Dosage and Administration
- 200 mg 5 times daily for 5 days for initial herpes simplex
- 400 mg 5 times daily for 5 days for immunocompromised patients (longer if new lesions appear during treatment or if healing is incomplete; increase dose to 800 mg 5 times daily for genital herpes in immunocompromised)
- 200 mg 4 times daily or 400 mg twice daily for prevention of recurrence of herpes simplex
- 200 to 400 mg 4 times daily for prophylactic treatment of herpes simplex in immunocompromised patients
- 800 mg 4 times daily for 5 days for chicken pox in adults and children over 40 kg
- 20 mg/kg (maximum 800 mg) per dose orally 4 times daily for 5 days for children below 40 kg
- 800 mg 5 times daily for 7 days for herpes zoster (shingles)
- 400 mg 5 times daily for 10 days for initial rectal (proctitis) herpes infections
- Dosage adjustment for severe renal impairment
Interaction
- Probenecid reduces Aciclovir excretion and increases plasma concentration and risk of toxicity
Contraindications
- Hypersensitivity to Aciclovir
Side Effects
- Rash
- Gastrointestinal disturbance
- Rise in bilirubin and liver-related enzymes
- Increase in blood urea and creatinine
- Decrease in hematological indices
- Headache
- Neurological reaction
- Fatigue
Pregnancy & Lactation
- Category B
- Caution for use during pregnancy unless benefit justifies the potential risk to the fetus
- Caution when administered to nursing mothers
Precautions & Warnings
- Administer with caution in patients with renal impairment
- Dose adjustment according to creatinine clearance
- Monitor neutrophil count at least twice weekly in neonates
Therapeutic Class
- Herpes simplex & Varicella-zoster virus infections
Storage Conditions
- Store below 25°C
- Protect from light and moisture
- Keep out of reach of children