Natoph 5% (Ophthalmic Suspension)

5 ml drop: ৳ 100.00

Medicine Details

Category Details
Generic Natamycin
Company Ibn sina pharmaceuticals ltd

Indications

  • Treatment of fungal blepharitis
  • Treatment of conjunctivitis
  • Treatment of keratitis caused by susceptible organisms

Pharmacology

  • Natamycin is a tetraene polyene antibiotic
  • Exerts antifungal effects by binding to sterols in the fungal cell membrane
  • Possesses in vitro activity against a variety of yeast and filamentous fungi

Dosage & Administration

  • Initial dosage is 1 drop instilled in the conjunctival sac at 1-2 hours interval for fungal keratitis
  • Frequency of application can be reduced to 1 drop 6-8 times daily after the first 3-4 days for fungal keratitis
  • Dosage for fungal blepharitis & conjunctivitis is 1 drop 4-6 times daily

Interaction

  • May increase spread of fungal eye infection when used with topical corticosteroid.

Contraindications

  • Contraindicated in individuals with a history of hypersensitivity to any of its component

Side Effects

  • Eye irritation
  • Eye discomfort
  • Eye edema
  • Conjunctival chemosis
  • Hyperemia

Pregnancy & Lactation

  • Pregnancy category C
  • Not known whether it can cause fetal harm when administered to pregnant women
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Do not touch dropper tip to any surface
  • Patients advised not to wear contact lenses if they have signs and symptoms of fungal blepharitis, conjunctivitis and keratitis
  • Continuation of therapy should be based on clinical re-evaluation and additional laboratory studies

Therapeutic Class

  • Ophthalmic antibacterial drugs

Storage Conditions

  • Store in a cool and dry place
  • Protect from light
  • Do not freeze
  • Do not use for longer than one month after first opening of the bottle

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