Tobrel 0.3% (Ophthalmic Solution)

Indications

• Topical antibiotic for external bacterial infections of the eye
• Treats infections caused by Gram-positive and Gram-negative bacteria

Pharmacology

• Bactericidal activity through active transport into sensitive bacterial cells
• Binds to bacterial ribosome, inhibiting protein synthesis

Dosage & Administration

• Ophthalmic ointment for mild to severe infections
• Ophthalmic solution for mild to severe infections
• Pediatric use safety and effectiveness not established

Interaction

• Exercised caution when given with neuromuscular blocking agents or ototoxic drugs

Contraindications

• Hypersensitivity to Tobramycin or any of the preparation ingredients

Side Effects

• Localized ocular toxicity
• Conjunctival erythema
• Hypersensitivity reactions such as lid itching and swelling

Pregnancy & Lactation

• Pregnancy category B
• Use during pregnancy if benefits outweigh risks
• Potential excretion into human milk
• Decision should be made for nursing continuation

Precautions & Warnings

• Minor sensitivity may occur
• Discontinue use if sensitivity reaction occurs
• Prolonged use may result in overgrowth of nonsusceptible organisms and fungi

Overdose Effects

• Symptoms similar to side effects

Therapeutic Class

• Ophthalmic antibacterial drugs

Storage Conditions

• Protect from light
• Store below 25°C in a dry place
• Use within 4 weeks after opening

Related Brands

• Cinarex 0.3% (Ophthalmic Solution) - beximco-pharmaceuticals-ltd
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• T-Drop 0.3% (Ophthalmic Solution) - reman-drug-laboratories-ltd