Egut 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Euro pharma ltd |
| Also available as |
Title
- Egut 10 mg Tablet
Categories
- Gastrointestinal Drugs
- Nausea & Vomiting Relief
- Parkinson's Disease Medication
Functions
- Relieves dyspeptic symptoms
- Reduces nausea and vomiting
- Enhances gastric emptying
- Regulates esophageal peristalsis
DosageRecommendation
- Adults: 10-20 mg every 6-8 hours daily
- Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
Usability
- Taken before meals and, if necessary, before retiring
- Not recommended for longer than 7 days without consulting a doctor
DosageForm
- Tablet
- Suspension
- Paediatric drops
- Suppositories
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach
- Facilitates gastric emptying
- Regulates contraction of the pylorus
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
SideEffects
- Transient intestinal cramps
- Extrapyramidal phenomena in rare cases
- Increase in plasma prolactin level
- Allergic reactions such as rash and urticaria
PregnancyLactation
- Should be used with caution during the first trimester of pregnancy
- Not recommended for nursing mothers unless benefits outweigh risks
PrecautionsWarnings
- Absolute caution in children due to risk of extra-pyramidal reactions
- Caution in patients with hepatic impairment
SpecialPopulations
- Caution in infants due to incomplete blood-brain barrier development
- Caution in patients with hepatic impairment
- Dosage adjustment in patients with severe renal insufficiency
OverdoseEffects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Recommendation of activated charcoal administration and close patient observation in case of overdosage
TherapeuticClass
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
StorageConditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
ChemicalStructure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure: Image provided in product details
CommonUsageTips
- Helps relieve nausea, vomiting, and indigestion
- Dizziness and sleepiness may occur
- Dry mouth may occur as a side effect
- Not recommended for longer than 7 days without consulting a doctor
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Interaction
- Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect of domperidone
- Antacids and antisecretory drugs should not be given simultaneously with domperidone
- Inhibition of CYP3A4 may result in increased plasma levels of domperidone
OverdoseManagement
- Administration of activated charcoal
- Close observation of patients
- Anticholinergic and antiparkinson drugs may be helpful in controlling extrapyramidal reactions
CompoundSummary
- Molecular Formula: C22H24ClN5O2
- Image: provided in product details