Dexagen 0.05% (Ophthalmic Ointment)

3 gm tube: ৳ 80.00

Medicine Details

Category Details
Generic Dexamethasone ophthalmic
Company General pharmaceuticals ltd
Also available as
Dexagen 01 eye drop

Indications

  • Treatment of allergic non-infectious blepharitis and conjunctivitis
  • Treatment of non-infectious keratitis, punctate keratitis, disciform keratitis
  • Treatment of inflammation of the anterior uvea (iritis, iridocyclitis)
  • Treatment of scleritis, episcleritis and myositis
  • Post-operative management of cataract, strabismus & other ocular surgeries

Pharmacology

  • Dexamethasone is a cortisone derivative with high anti-inflammatory activity
  • Anti-allergic, anti-exudative and anti-proliferative properties
  • Therapeutic concentrations in cornea and aqueous humor after local application
  • Inhibition of phospholipase A2 and prostaglandin synthesis
  • Inhibition of neutrophil infiltration into the site of inflammation

Dosage & Administration

  • Instill 1 drop of dexamethasone ophthalmic solution into the conjunctival sac 3-5 times per day
  • Acute cases: up to 1 drop every hour if necessary
  • Apply a small amount of dexamethasone ophthalmic ointment into the conjunctival sac 3-4 times per day
  • Keep eyes closed for 1 to 2 minutes after applying the ointment

Interaction

  • Specific drug interaction studies not conducted with Dexagen

Contraindications

  • Injuries and ulcerating processes of the cornea
  • Purulent infections of the conjunctiva and eyelids
  • Tuberculosis, mycosis, glaucoma

Side Effects

  • Reversible rise in intraocular pressure in predisposed patients
  • Regular pressure measurements are essential

Pregnancy & Lactation

  • Animal experiments have shown adverse effects on the fetus
  • Usage during pregnancy only if potential benefit justifies potential risk

Precautions & Warnings

  • Corticosteroids may mask, activate or aggravate an eye infection
  • If no improvement is seen after a few days, consider alternative treatment
  • Avoid touching dropper tip to any surface to prevent contamination

Overdose Effects

  • Overdose through local or accidental oral administration is not likely

Storage Conditions

  • Store at room temperature & protect from light
  • Use contents within one month after opening

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