Emedon 10 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Domperidone maleate
Company Cosmic pharma ltd

Title

Emedon 10 mg Tablet

Categories

  • Medicine
  • Health & Wellness

Description

Emedon 10 mg Tablet is a dopamine antagonist medication used to treat nausea and vomiting.

Dosage

  • 10-20 mg for adults every 6-8 hours daily
  • 2-4 ml suspension/10 kg body weight for children every 6-8 hours daily

Administration

Should be taken 15-30 minutes before meals and, if necessary, before retiring.

Indications

  • Dyspeptic symptom complex
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

Domperidone blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach, restoring normal motility and tone of the upper gastrointestinal tract.

Interaction

  • May be affected by anticholinergic drugs
  • Antacids and antisecretory drugs lower its oral bioavailability
  • Metabolism influences by CYP3A4
  • May influence the absorption of concomitantly orally administered drugs

Contraindications

  • Known hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage, mechanical obstruction, or perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Rare allergic reactions

Pregnancy & Lactation

  • Use only if justified during the first trimester of pregnancy
  • Excreted in breast milk at lower concentrations than in plasma

Precautions

  • Caution in children due to risk of extra-pyramidal reactions
  • Caution in patients with hepatic impairment

Use in Special Populations

  • Great caution needed in infants
  • Caution in patients with hepatic impairment
  • Dosing adjustment recommended in severe renal insufficiency

Overdose Effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

Therapeutic Class

Motility Stimulants, Motility stimulants/Dopamine antagonist, Prokinetic drugs

Storage Conditions

Store below 30°C, Protected from light & moisture. Keep out of children's reach.

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

Commonly Asked Questions

  • What is Emedon 10 mg Tablet used for?
  • Emedon 10 mg Tablet helps relieve nausea, vomiting and indigestion.

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