Decalor 0.1%+0.5% (Ophthalmic Solution)

5 ml drop: ৳ 55.00

Medicine Details

Category	Details
Generic	Dexamethasone chloramphenicol
Company	Jayson pharmaceuticals ltd

Title and Categories

Decalor Ophthalmic Drops
Eye and Ear Medication
Ophthalmic Steroid - Antibiotic Combined Preparations

Dimensions

N/A

Color Options

Clear liquid

Functions

Treatment of bacterial conjunctivitis
Treatment of corneal ulcers
Treatment of otitis externa
Treatment of otitis media
Treatment of chronic suppurative otitis media

Materials

Dexamethasone, Chloramphenicol, Excipients

Technical Specifications

Glucocorticoid action of Dexamethasone
Bacteriostatic antibiotic action of Chloramphenicol
Rapid absorption after oral administration
Systemic effects from topical application

Design Elements

Eye and ear medication, Ophthalmic solution

Usability Features

Topical use
Easy-to-administer dropper
Dosage regimen for different eye conditions
Decreasing frequency as warranted by improvement in clinical signs

Indications

Treatment for acute purulent conjunctivitis
Treatment for fresh inflammation of corneal layers
Treatment for corneal ulceration
Treatment for keratitis disciformis
Treatment for post-herpetic keratitis
Treatment for allergic conjunctivitis
Treatment for allergic blepharitis
Treatment for iritis
Treatment for uveitis
Treatment for corneal injury from chemical radiation or thermal burns
Treatment for penetration of foreign bodies
Treatment for otitis externa
Treatment for otitis media
Treatment for chronic suppurative otitis media

Pharmacology

Anti-inflammatory action of Dexamethasone
Anti-allergic action of Dexamethasone
Broad spectrum bacteriostatic action of Chloramphenicol
Binding to bacterial ribosomes
Inhibition of bacterial protein synthesis

Dosage and Administration

Dosage regimen for bacterial conjunctivitis
Dosage regimen for corneal ulcers
Initial dosage for ear infections
Gradual frequency decrease based on improvement

Interaction

Potential interaction with anticoagulants like warfarin
Inhibition action with Phenobarbital
Reduced efficacy with concomitant administration of phenytoin, phenobarbitone, ephedrine and rifampicin

Contraindications

Contraindicated in epithelial herpes simplex cornealis
Contraindicated in fungal, viral, tuberculous and other eye infections
Contraindicated in glaucoma
Contraindicated in myelosuppression during previous exposure to Chloramphenicol
Contraindicated in hypersensitivity to Chloramphenicol & Dexamethasone Phosphate

Side Effects

Transient ocular burning or discomfort
Stinging, redness, itching
Conjunctivitis, foreign body sensation
Photophobia, blurred vision, dryness, eye pain
Allergic sensitization
Elevation of intraocular pressure
Possible development of glaucoma
Optic nerve damage
Posterior subcapsular cataract formation

Pregnancy and Lactation

Potential risk to the fetus, caution in nursing mothers

Precautions and Warnings

Consideration of persistent fungal infections
Monitoring for posterior subcapsular cataract formation
Intraocular pressure monitoring
Overgrowth of non-susceptible organisms
Discontinuation and alternative therapy for new infections

Therapeutic Class

Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

Cool and dry place, away from light, keep out of reach of children, do not use after 30 days of first opening