Decalor 0.1%+0.5% (Ophthalmic Solution)

Title and Categories

• Decalor Ophthalmic Drops
• Eye and Ear Medication
• Ophthalmic Steroid - Antibiotic Combined Preparations

Dimensions

N/A

Color Options

Clear liquid

Functions

• Treatment of bacterial conjunctivitis
• Treatment of corneal ulcers
• Treatment of otitis externa
• Treatment of otitis media
• Treatment of chronic suppurative otitis media

Materials

Dexamethasone, Chloramphenicol, Excipients

Technical Specifications

• Glucocorticoid action of Dexamethasone
• Bacteriostatic antibiotic action of Chloramphenicol
• Rapid absorption after oral administration
• Systemic effects from topical application

Design Elements

Eye and ear medication, Ophthalmic solution

Usability Features

• Topical use
• Easy-to-administer dropper
• Dosage regimen for different eye conditions
• Decreasing frequency as warranted by improvement in clinical signs

Indications

• Treatment for acute purulent conjunctivitis
• Treatment for fresh inflammation of corneal layers
• Treatment for corneal ulceration
• Treatment for keratitis disciformis
• Treatment for post-herpetic keratitis
• Treatment for allergic conjunctivitis
• Treatment for allergic blepharitis
• Treatment for iritis
• Treatment for uveitis
• Treatment for corneal injury from chemical radiation or thermal burns
• Treatment for penetration of foreign bodies
• Treatment for otitis externa
• Treatment for otitis media
• Treatment for chronic suppurative otitis media

Pharmacology

• Anti-inflammatory action of Dexamethasone
• Anti-allergic action of Dexamethasone
• Broad spectrum bacteriostatic action of Chloramphenicol
• Binding to bacterial ribosomes
• Inhibition of bacterial protein synthesis

Dosage and Administration

• Dosage regimen for bacterial conjunctivitis
• Dosage regimen for corneal ulcers
• Initial dosage for ear infections
• Gradual frequency decrease based on improvement

Interaction

• Potential interaction with anticoagulants like warfarin
• Inhibition action with Phenobarbital
• Reduced efficacy with concomitant administration of phenytoin, phenobarbitone, ephedrine and rifampicin

Contraindications

• Contraindicated in epithelial herpes simplex cornealis
• Contraindicated in fungal, viral, tuberculous and other eye infections
• Contraindicated in glaucoma
• Contraindicated in myelosuppression during previous exposure to Chloramphenicol
• Contraindicated in hypersensitivity to Chloramphenicol & Dexamethasone Phosphate

Side Effects

• Transient ocular burning or discomfort
• Stinging, redness, itching
• Conjunctivitis, foreign body sensation
• Photophobia, blurred vision, dryness, eye pain
• Allergic sensitization
• Elevation of intraocular pressure
• Possible development of glaucoma
• Optic nerve damage
• Posterior subcapsular cataract formation

Pregnancy and Lactation

Potential risk to the fetus, caution in nursing mothers

Precautions and Warnings

• Consideration of persistent fungal infections
• Monitoring for posterior subcapsular cataract formation
• Intraocular pressure monitoring
• Overgrowth of non-susceptible organisms
• Discontinuation and alternative therapy for new infections

Therapeutic Class

Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

Cool and dry place, away from light, keep out of reach of children, do not use after 30 days of first opening

Related Brands

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• Cloram-D 0.1%+0.5% (Ophthalmic Solution) - ibn-sina-pharmaceuticals-ltd