Dexacol 0.1%+0.5% (Ophthalmic Solution)
5 ml drop: ৳ 70.21
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone chloramphenicol |
| Company | Osl pharma limited |
Indications
- Treatment of acute purulent conjunctivitis
- Treatment of corneal ulcer
- Treatment of keratitis disciformis
- Treatment of post-herpetic keratitis
- Treatment of allergic conjunctivitis
- Treatment of allergic blepharitis
- Treatment of iritis
- Treatment of uveitis
- Treatment of corneal injury from chemical radiation or thermal burns
- Treatment of otitis externa
- Treatment of otitis media
- Treatment of chronic suppurative otitis media
Pharmacology
- Dexamethasone has anti-inflammatory action
- Dexamethasone has anti-allergic action
- Chloramphenicol is a broad spectrum bacteriostatic antibiotic
- Chloramphenicol is active against gram-negative organisms
- Chloramphenicol is active against gram-positive organisms
- Chloramphenicol inhibits bacterial protein synthesis
Dosage & Administration
- Recommended dosage regimen for bacterial conjunctivitis
- Recommended dosage regimen for corneal ulcers
- Recommended dosage regimen for otitis externa
- Recommended dosage regimen for otitis media
- Care should be taken not to discontinue therapy prematurely
Interaction
- Potential interaction with anticoagulants
- Inhibition of Chloramphenicol action by Phenobarbital
- Reduced efficacy of Dexamethasone with phenytoin
- Reduced efficacy of Dexamethasone with phenobarbitone
- Reduced efficacy of Dexamethasone with ephedrine
- Reduced efficacy of Dexamethasone with rifampicin
Contraindications
- Contraindicated in epithelial herpes simplex cornealis
- Contraindicated in fungal infections of the eye
- Contraindicated in viral infections of the eye
- Contraindicated in tuberculous infections of the eye
- Contraindicated in glaucoma
- Contraindicated in myelosuppression during previous exposure to Chloramphenicol
- Contraindicated in hypersensitivity to Chloramphenicol & Dexamethasone
Side Effects
- Transient ocular burning or discomfort
- Stinging
- Redness
- Itching
- Conjunctivitis
- Foreign body sensation
- Photophobia
- Blurred vision
- Dryness
- Eye pain
- Allergic sensitization
- Elevation of intraocular pressure
- Development of glaucoma
- Optic nerve damage
- Posterior subcapsular cataract formation
Pregnancy & Lactation
- Use during pregnancy if potential benefit justifies potential risk
- Caution when administered to nursing mothers
Precautions & Warnings
- Consideration of persistent fungal infections of the cornea
- Monitoring of intraocular pressure
- Possibility of posterior subcapsular cataract formation
- Possibility of glaucoma with optic nerve damage
- Possibility of overgrowth of non-susceptible organisms
Therapeutic Class
- Ophthalmic steroid - antibiotic combined preparations
Storage Conditions
- Keep in cool and dry place
- Keep away from light
- Keep out of the reach of children
- Do not use after 30 days of first opening
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