Dexagen C 0.1%+0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.21

Medicine Details

Indications

  • Acute purulent conjunctivitis
  • Inflammation
  • Corneal ulceration
  • Keratitis disciformis
  • Post-herpetic keratitis
  • Allergic conjunctivitis
  • Allergic blepharitis
  • Iritis
  • Uveitis
  • Corneal injury
  • Otitis externa
  • Otitis media
  • Suppurative otitis media

Pharmacology

  • Anti-inflammatory action
  • Anti-allergic action
  • Topical treatment
  • Rapid absorption
  • Half-life of about 190 minutes
  • Bacteriostatic antibiotic
  • Broad spectrum activity
  • Inhibition of bacterial protein synthesis

Dosage & Administration

  • Dosage regimen for bacterial conjunctivitis
  • Dosage regimen for corneal ulcers
  • Dosage regimen for otitis externa
  • Initial dosage of 2 to 3 drops every 2 to 3 hours

Interaction

  • Interaction with anticoagulants
  • Inhibition by Phenobarbital
  • Reduced efficacy with phenytoin
  • Reduced efficacy with phenobarbitone
  • Reduced efficacy with ephedrine
  • Reduced efficacy with rifampicin

Contraindications

  • Epithelial herpes simplex cornealis
  • Fungal infections of the eye
  • Viral infections of the eye
  • Tuberculous infections of the eye
  • Glaucoma
  • Myelosuppression
  • Hypersensitivity

Side Effects

  • Ocular burning or discomfort
  • Stinging
  • Redness
  • Itching
  • Conjunctivitis
  • Foreign body sensation
  • Photophobia
  • Blurred vision
  • Dryness
  • Eye pain
  • Allergic sensitization
  • Elevation of intraocular pressure
  • Glaucoma
  • Optic nerve damage
  • Cataract formation

Pregnancy & Lactation

  • No adequate and well-controlled studies
  • Caution during pregnancy
  • Exercised caution when administered to nursing mother

Precautions & Warnings

  • Persistent fungal infections
  • Prolonged corticosteroid dosing
  • Posterior subcapsular cataract formation
  • Glaucoma with optic nerve damage
  • Intraocular pressure monitoring
  • Prolonged use of antibiotics
  • Overgrowth of non-susceptible organisms
  • Discontinuation if new infections appear

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Cool and dry place
  • Away from light
  • Out of the reach of children
  • Do not use after 30 days of first opening

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