Dexonex-C 0.1%+0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.21

Medicine Details

Category Details
Generic Dexamethasone chloramphenicol
Company Square pharmaceuticals plc

Categories

  • Ophthalmic Medication
  • Ear Medication
  • Antibiotic Eye Drops
  • Corticosteroid Eye Drops

Indications

  • Treatment of acute purulent conjunctivitis
  • Treatment of corneal ulceration
  • Used in keratitis disciformis
  • Treatment of allergic conjunctivitis
  • Treatment of acute and chronic iritis
  • Treatment of otitis externa
  • Treatment of otitis media
  • Used in chronic suppurative otitis media

Pharmacology

  • Dexamethasone has anti-inflammatory and anti-allergic action
  • Chloramphenicol is a broad spectrum bacteriostatic antibiotic

Dosage & Administration

  • For bacterial conjunctivitis: 1-2 drops every 2 hours for 2 days, then 1-2 drops every 4 hours for 5 days
  • For corneal ulcers: 2 drops every 15 minutes for the first 6 hours, then every 30 minutes for the first day, followed by hourly instillation on the second day, and every 4 hours from day 3 to 14
  • For otitis: 2-3 drops every 2-3 hours initially, with frequency decrease as warranted by improvement

Interaction

  • Potential increase in anticoagulant effect when absorbed with warfarin
  • Inhibition by Phenobarbital
  • Reduced efficacy with concomitant administration of phenytoin, phenobarbitone, ephedrine, and rifampicin

Contraindications

  • Epithelial herpes simplex cornealis
  • Fungal, viral, tuberculous, and other eye infections
  • Glaucoma
  • Myelosuppression during previous chloramphenicol exposure
  • Hypersensitivity to chloramphenicol or dexamethasone phosphate, or any other ingredients

Side Effects

  • Transient ocular burning or discomfort
  • Stinging, redness, itching, and conjunctivitis
  • Foreign body sensation, photophobia, and blurred vision
  • Dryness and eye pain
  • Allergic sensitization
  • Elevation of intraocular pressure with possible development of glaucoma
  • Infrequent optic nerve damage
  • Posterior subcapsular cataract formation

Pregnancy & Lactation

  • Caution advised in pregnancy due to lack of well-controlled studies
  • Caution advised in nursing mothers

Precautions & Warnings

  • Consideration of persistent fungal infections
  • Monitoring for posterior subcapsular cataract formation and glaucoma with optic nerve damage
  • Monitoring of intraocular pressure
  • Potential for overgrowth of non-susceptible organisms with prolonged antibiotic use

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Keep in a cool, dry place away from light
  • Keep out of the reach of children
  • Do not use after 30 days of first opening

Related Brands