Ocubac-D 0.1%+0.5% (Ophthalmic Solution)
5 ml drop: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone chloramphenicol |
| Company | Apex pharmaceuticals ltd |
Indications
- Treatment of purulent conjunctivitis
- Treatment of corneal ulceration
- Treatment of keratitis disciformis
- Treatment of post-herpetic keratitis
- Treatment of allergic conjunctivitis
- Treatment of allergic blepharitis
- Treatment of iritis
- Treatment of uveitis
- Treatment of corneal injury
- Treatment of otitis externa
- Treatment of otitis media
- Treatment of suppurative otitis media
Pharmacology
- Dexamethasone is a glucocorticoid
- Anti-inflammatory and anti-allergic action
- Rapid absorption after oral administration
- Chloramphenicol is a broad spectrum bacteriostatic antibiotic
- Active against gram-negative and gram-positive organisms
- Inhibition of bacterial protein synthesis
Dosage & Administration
- Dosage regimen for bacterial conjunctivitis
- Dosage regimen for corneal ulcers
- Dosage regimen for otitis externa
- Dosage regimen for otitis media
- Frequency adjustment based on clinical signs
Interaction
- Potential interaction with anticoagulants
- Inhibition by Phenobarbital
- Therapeutic efficacy reduction with phenytoin
- Therapeutic efficacy reduction with phenobarbitone
- Therapeutic efficacy reduction with ephedrine
- Therapeutic efficacy reduction with rifampicin
Contraindications
- Contraindicated in herpes simplex cornealis
- Contraindicated in fungal infections of the eye
- Contraindicated in viral infections of the eye
- Contraindicated in tuberculous infections of the eye
- Contraindicated in glaucoma
- Contraindicated in myelosuppression
- Contraindicated in hypersensitivity to Chloramphenicol
- Contraindicated in hypersensitivity to Dexamethasone Phosphate
Side Effects
- Transient ocular burning or discomfort
- Stinging
- Redness
- Itching
- Conjunctivitis
- Foreign body sensation
- Photophobia
- Blurred vision
- Dryness
- Eye pain
- Allergic sensitization
- Elevation of intraocular pressure
- Possible development of glaucoma
- Optic nerve damage
- Posterior subcapsular cataract formation
Pregnancy & Lactation
- Use during pregnancy requires assessment of potential benefits and risks
- Caution required during lactation
Precautions & Warnings
- Consideration of persistent fungal infections of the cornea
- Prolonged use may result in cataract formation
- Prolonged use may result in glaucoma
- Intraocular pressure monitoring needed
- Possible overgrowth of non-susceptible organisms
- Discontinuation and alternative therapy for new infections
Therapeutic Class
- Ophthalmic steroid - antibiotic combined preparations
Storage Conditions
- Store in cool and dry place
- Protect from light
- Keep out of the reach of children
- Do not use after 30 days of first opening
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