Optadex 0.1%+0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.26

Medicine Details

Title

  • Optadex Ophthalmic Solution

Category

  • Medicine
  • Ophthalmic Solution
  • Pharmaceutical

Description

  • Optadex is an ophthalmic solution indicated for the treatment of various eye conditions such as conjunctivitis, keratitis, uveitis, and corneal injuries. It also treats otitis externa and media in the ear. The solution contains dexamethasone, a glucocorticoid with anti-inflammatory and anti-allergic properties, and chloramphenicol, a broad-spectrum bacteriostatic antibiotic.

Dimensions

N/A

Color Options

  • Clear solution

Functions

  • Anti-inflammatory
  • Antibacterial
  • Treats purulent conjunctivitis
  • Treats otitis externa and media

Materials

  • Dexamethasone
  • Chloramphenicol
  • Phosphate

Technical Specifications

  • Rapid absorption after administration
  • Half-life of dexamethasone is about 190 minutes
  • Bacteriostatic action of chloramphenicol
  • Binding to bacterial ribosomes

Design Elements

  • Ophthalmic solution
  • Topical application
  • Combination of steroid and antibiotic

Usability Features

  • Easy to administer with dropper
  • Storage period of 30 days after opening

Dosage & Administration

  • Dosage regimen for bacterial conjunctivitis
  • Dosage regimen for corneal ulcers
  • Dosage regimen for otitis externa and media

Interaction

  • Increased effect with anticoagulants
  • Inhibition with phenobarbital
  • Reduced efficacy with phenytoin, phenobarbitone, ephedrine, and rifampicin

Contraindications

  • Epithelial herpes simplex cornealis
  • Fungal, viral, tuberculous infections of the eye
  • Glaucoma
  • Myelosuppression during previous exposure to chloramphenicol
  • Hypersensitivity to chloramphenicol and dexamethasone phosphate

Side Effects

  • Ocular burning or discomfort
  • Stinging
  • Redness
  • Itching
  • Conjunctivitis
  • Photophobia
  • Blurred vision
  • Dryness
  • Eye pain
  • Elevation of intraocular pressure
  • Possible development of glaucoma
  • Optic nerve damage
  • Posterior subcapsular cataract formation
  • Allergic sensitization with local use of chloramphenicol

Pregnancy & Lactation

  • Use during pregnancy if potential benefit justifies potential risk
  • Caution during nursing

Precautions & Warnings

  • Persistent fungal infections possibility
  • Prolonged use may result in cataract formation and glaucoma
  • Intraocular pressure monitoring needed
  • Overgrowth of non-susceptible organisms with prolonged antibiotic use
  • Discontinue if new infections appear

Therapeutic Class

  • Ophthalmic steroid-antibiotic combined preparations

Storage Conditions

  • Cool and dry place
  • Away from light
  • Keep out of reach of children

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