Ramdex 0.1%+0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.21

Medicine Details

Indications

  • Treatment of acute purulent conjunctivitis
  • Treatment of corneal ulceration
  • Management of allergic conjunctivitis
  • Treatment of keratitis disciformis
  • Management of chronic suppurative otitis media
  • Treatment of otitis externa
  • Management of chronic anterior uveitis

Pharmacology

  • Dexamethasone is a glucocorticoid with anti-inflammatory and anti-allergic action
  • Chloramphenicol is a broad-spectrum bacteriostatic antibiotic

Dosage & Administration

  • Dosage regimen for bacterial conjunctivitis
  • Dosage regimen for corneal ulcers
  • Dosage regimen for otitis externa
  • Dosage regimen for otitis media
  • Recommended drops and instillation frequency

Interaction

  • Potential interaction with anticoagulants like warfarin
  • Inhibition of chloramphenicol by phenobarbital
  • Reduced efficacy with concomitant administration of phenytoin

Contraindications

  • Contraindicated in epithelial herpes simplex cornealis
  • Contraindicated in fungal, viral, tuberculous infections of the eye
  • Contraindicated in glaucoma
  • Contraindicated in myelosuppression during previous exposure to chloramphenicol

Side Effects

  • Transient ocular burning or discomfort
  • Stinging, redness, itching
  • Conjunctivitis, foreign body sensation
  • Photophobia, blurred vision, dryness, eye pain
  • Elevation of intraocular pressure, glaucoma, optic nerve damage
  • Posterior subcapsular cataract formation

Pregnancy & Lactation

  • Caution advised during pregnancy
  • Caution advised while nursing

Precautions & Warnings

  • Consideration of persistent fungal infections of the cornea
  • Monitoring for posterior subcapsular cataract formation and glaucoma
  • Intraocular pressure monitoring
  • Risk of overgrowth of non-susceptible organisms

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Cool and dry storage
  • Protection from light
  • Expiry after 30 days of opening

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