Beuflox-D 0.3%+0.1% (Ophthalmic Solution)

5 ml drop: ৳ 75.00

Medicine Details

Category Details
Generic Ciprofloxacin dexamethasone
Company Incepta pharmaceuticals ltd

Indications

  • Treatment of steroid responsive inflammatory ocular conditions
  • Post-operative inflammation
  • Ear infections accompanied by inflammation
  • Otitis externa
  • Acute and chronic otitis media

Pharmacology

  • Dexamethasone has anti-inflammatory and anti-allergic action
  • Ciprofloxacin has in vitro activity against a wide range of gram-negative and gram-positive organisms

Dosage & Administration

  • Eye: Instill 1 drop every 4-6 hours, with potential dosage increase in initial 24-48 hours
  • Ear (Acute otitis media): 4 drops instilled into affected ear 2 times daily for 7 days
  • Ear (Acute otitis externa): 4 drops instilled into affected ear 2 times daily for 7 days
  • Pediatric use safety and effectiveness below 1 year not established

Interaction

  • Specific drug interaction studies not conducted with ophthalmic Ciprofloxacin and Dexamethasone
  • Quinolones may elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance effects of oral anticoagulant warfarin, and transiently elevate serum creatinine in patients receiving cyclosporin concomitantly

Contraindications

  • Hypersensitivity to any ingredient of the product
  • Herpes simplex and other viral conditions
  • Mycosis
  • Glaucoma
  • Newborn babies
  • Fungal diseases of ocular or auricular structures

Side Effects

  • Transient ocular burning or discomfort
  • Stinging
  • Redness
  • Itching
  • Conjunctivitis/keratitis
  • Periocular/facial edema
  • Elevation of intraocular pressure (IOP)
  • Optic nerve damage
  • Posterior subcapsular cataract formation
  • Delayed wound healing
  • Ear pain
  • Irritability
  • Dizziness
  • Erythema

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Caution when using in nursing mothers due to unknown excretion in human milk

Precautions & Warnings

  • Consider possibility of fungal infections of the cornea after long-term steroid dosing
  • Prolonged use of antibiotic may result in overgrowth of non-susceptible organisms
  • Prolonged use of topical ophthalmic steroids may result in glaucoma and cataract formation
  • Intraocular pressure should be routinely monitored

Therapeutic Class

  • Aural steroid & antibiotic combined preparations

Storage Conditions

  • Store in a cool and dry place, away from light
  • Keep out of reach of children
  • Shake well before each use
  • Use within 30 days after first opening
  • Close bottle strongly immediately after use

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